*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6594000
CHEMICAL NAME           : Luteinizing hormone-releasing factor(pig),
                          3-(3-(1-naphthalenyl)-L-alanine)-6-(3-(2-
                          naphthalenyl)-D-alanine)-9-(N-ethyl-L-prolinamide)-10
                          -deglycinamide-, monoacetate (salt)
CAS REGISTRY NUMBER     : 82318-11-4
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C68-H85-N15-O12.C2-H4-O4
MOLECULAR WEIGHT        : 1396.74
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (Nal(1)(sup 3)-D-Nal(2)(sup 6)-Pro-NHEt(sup 9))-LHRH acetate
   * (Nal(1)(sup 3)-D-Nal(2)(sup 6)-Pro-NHEt(Sup 9))-luteinizing  
   hormone-releasing hormone acetate
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 22400 ng/kg
SEX/DURATION            : female 14 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 25,795,1982
 
                            *** END OF RECORD ***