*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OK6708000
CHEMICAL NAME           : Luteinizing hormone-releasing factor(pig),
                          1-de(5-oxo-L-proline)-2-(N-((phenylmethoxy)
                          carbonyl)-O-(phenylmethyl)-L-serine)-6-D-phenylalanin
                          e-, hydrochloride, hydrate (2:3:8)
CAS REGISTRY NUMBER     : 63929-61-3
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C69-H86-N14-O14.3/2Cl-H.4H2-O
MOLECULAR WEIGHT        : 1462.27
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Z-(Ser(Bz1)(sup 1)-des-His(sup 2)-D-Phe(sup 6))-LHRH hydrochloride  
   hydrate (2:3:8)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 90 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 22,935,1979
 
                            *** END OF RECORD ***