*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OH3160000
CHEMICAL NAME           : Leucine,
                          N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)b
                          enzoyl)-, L-
CAS REGISTRY NUMBER     : 68352-98-7
LAST UPDATED            : 199610
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H26-N8-O3
MOLECULAR WEIGHT        : 438.55
WISWESSER LINE NOTATION : T66 BN DN GN JNJ CZ EZ H1N1&R DVMYVQ1Y1&1 -L
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-leucine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 184 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 29,43,1982
 
                            *** END OF RECORD ***