*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OH2913000
CHEMICAL NAME           : L-Leucine,
                          N-(3-amino-2-hydroxy-4-(4-hydroxyphenyl)-1-oxobutyl)-
                          , (S-(R*,S*))-
CAS REGISTRY NUMBER     : 70267-76-4
LAST UPDATED            : 199312
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H24-N2-O5
MOLECULAR WEIGHT        : 324.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (-)-N-(2S,3R)-3-(Amino-2-hydroxy-4-(4'-hydroxyphenyl)butyryl)-L-leucine
   * N-(3-Amino-2-hydroxy-4-(4-hydroxyphenyl)-1-oxobutyl)-L-leucine  
   (S-(R*,S*))-
   * p-Hydroxybestatin
   * p-Hydroxyubenimex
   * OH-Ubenimex
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1862,1988
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 41,1862,1988
 
                            *** END OF RECORD ***