*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OD2350000
CHEMICAL NAME           : Lactamide,
                          N-(7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-1
                          6-oxabicyclo(13.2.2)
                          nonadeca-3,5,9,11-tetraen-2-yl)-, 13-acetate,
                          (all-E)-(1S,2R,7S,13S,15R,19R)-(-)-
CAS REGISTRY NUMBER     : 23498-36-4
LAST UPDATED            : 199112
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C27-H37-N-O8
MOLECULAR WEIGHT        : 503.65
WISWESSER LINE NOTATION : T6-17- A B AOV DV IU KU OUTJ C1 E1 HOV1 K1 NQ Q1
                          SMVYQ1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic T-2636D
   * Lankacidinol A
   * Lankacidinol 14-acetate
   * P-2636 D
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 41,81,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 26,647,1973
 
                            *** END OF RECORD ***