*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : OC4500000
CHEMICAL NAME           : Kosotoxin
CAS REGISTRY NUMBER     : 1400-16-4
LAST UPDATED            : 199312
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Kosins from hagenia abyssinica
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPBADA Journal of Pharmaceutical and Biomedical Analysis.  (Pergamon Press
   Ltd., Headington Hill Hall, Oxford, OX3 0BW, United Kingdom)  V.1-    1983-
   Volume(issue)/page/year: 10,555,1992
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   JPBADA Journal of Pharmaceutical and Biomedical Analysis.  (Pergamon Press
   Ltd., Headington Hill Hall, Oxford, OX3 0BW, United Kingdom)  V.1-    1983-
   Volume(issue)/page/year: 10,555,1992
 
                            *** END OF RECORD ***