*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NY2937000
CHEMICAL NAME           : Isoxazole, 5-phenyl-3-(2-(1-pyrrolidinyl)ethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 1219-21-2
LAST UPDATED            : 199007
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H18-N2-O.Cl-H
MOLECULAR WEIGHT        : 278.81
WISWESSER LINE NOTATION : T5NOJ CR& E2- AT5NTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Isoxazole, 5-phenyl-3-(2-pyrrolidinoethyl)-, hydrochloride
   * 3-(2-Pyrrolidinoethyl)-5-phenylisoxazole hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Nutritional and Gross Metabolic - body temperature decrease
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,411,1967
 
                            *** END OF RECORD ***