*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8157480
CHEMICAL NAME           : Isothiazolo(4',3':4,5)thieno(3,2-d)-1,2,3-triazin-4(1
                          H)-one, 8-(((4-fluorophenyl)methyl)thio)-
CAS REGISTRY NUMBER     : 135489-01-9
BEILSTEIN REFERENCE NO. : 4271132
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H7-F-N4-O-S3
MOLECULAR WEIGHT        : 350.42
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   8-(((4-Fluorophenyl)methyl)thio)isothiazolo(4',3':4,5)thieno(3,2-d)-1,2,
     3-triazin-4(1H)-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella
   Postale 227, 27100 Pavia, Italy)  V.44-   1989-  Volume(issue)/page/year:
   46,33,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella
   Postale 227, 27100 Pavia, Italy)  V.44-   1989-  Volume(issue)/page/year:
   46,33,1991
 
                            *** END OF RECORD ***