*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8157353
CHEMICAL NAME           : Isothiazolo(5,4-b)pyridin-3(2H)-one,
                          4,6-dimethyl-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)
                          butyl)-
CAS REGISTRY NUMBER     : 173284-33-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H26-N6-O-S
MOLECULAR WEIGHT        : 398.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-4,6-dimethyl-3-oxoisothiazo
     lo(5,4-b)pyridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 810 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella
   Postale 227, 27100 Pavia, Italy)  V.44-   1989-  Volume(issue)/page/year:
   50,769,1995
 
                            *** END OF RECORD ***