*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8156900
CHEMICAL NAME           : 4-Isothiazolin-3-one, 2-octyl-
CAS REGISTRY NUMBER     : 26530-20-1
OTHER CAS REGISTRY NOS. : 12673-72-2
BEILSTEIN REFERENCE NO. : 1211137
LAST UPDATED            : 199710
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C11-H19-N-O-S
MOLECULAR WEIGHT        : 213.37
WISWESSER LINE NOTATION : T5SNVJ B8
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * 3(2H)-Isothiazolone, 2-octyl-
   * Kathon LP preservative
   * Kathon SP 70
   * Micro-chek 11
   * Micro-chek 11D
   * Micro-chek skane
   * Octhilinone
   * 2-Octyl-4-isothiazolin-3-one
   * 2-Octyl-3(2H)-isothiazolone
   * Pancil
   * Pancil-T
   * RH 893
   * Skane M8
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 500 mg/24H
REFERENCE :
   MosJN# Personal Communication from J.N. Moss, Toxicology Dept., Rohm and
   Haas Co., Spring House, PA 19477, Aug. 15, 1979  Volume(issue)/page/year:
   15AUG1979
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg
REACTION SEVERITY       : Severe
REFERENCE :
   MosJN# Personal Communication from J.N. Moss, Toxicology Dept., Rohm and
   Haas Co., Spring House, PA 19477, Aug. 15, 1979  Volume(issue)/page/year:
   15AUG1979
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MosJN# Personal Communication from J.N. Moss, Toxicology Dept., Rohm and
   Haas Co., Spring House, PA 19477, Aug. 15, 1979  Volume(issue)/page/year:
   15AUG1979
 
TYPE OF TEST            : LC - Lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2 gm/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JALCAQ Journal of the American Leather Chemists' Association.  (American
   Leather Chemists' Association, Tanners' Council Research Laboratory, Room
   10, Campus Station, Cincinnati, OH 45221) V.1-    1906-
   Volume(issue)/page/year: 74,322,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 690 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MosJN# Personal Communication from J.N. Moss, Toxicology Dept., Rohm and
   Haas Co., Spring House, PA 19477, Aug. 15, 1979  Volume(issue)/page/year:
   15AUG1979

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1443
       No. of Facilities: 237 (estimated)
       No. of Industries: 4
       No. of Occupations: 7
       No. of Employees: 2782 (estimated)
       No. of Female Employees: 23 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***