*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8155750
CHEMICAL NAME           : 4-Isothiazolecarboxylic acid, 5-chloro-3-methyl-,
                          3-(4-methyl-1-piperazinyl)propyl ester
CAS REGISTRY NUMBER     : 22131-65-3
LAST UPDATED            : 198608
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H20-Cl-N3-O2-S
MOLECULAR WEIGHT        : 317.87
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Chloro-3-methyl-4-isothiazolecarboxylic acid  
   3-(4-methyl-1-piperazinyl)propyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2288 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - irritability
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 263 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - irritability
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
                            *** END OF RECORD ***