*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX8155700
CHEMICAL NAME           : 4-Isothiazolecarboxylic acid, 5-chloro-3-methyl-,
                          2-(dimethylamino)ethyl ester
CAS REGISTRY NUMBER     : 22164-92-7
BEILSTEIN REFERENCE NO. : 1110510
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H13-Cl-N2-O2-S
MOLECULAR WEIGHT        : 248.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Chloro-3-methyl-4-isothiazolecarboxylic acid 2-(dimethylamino)ethyl  
   ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2194 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   21,329,1973
 
                            *** END OF RECORD ***