*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX6037220
CHEMICAL NAME           : 3(2H)-Isoquinolinone,
                          1,4-dihydro-6,7-dimethoxy-4-((dimethylamino)methylene
                          )-
CAS REGISTRY NUMBER     : 78893-39-7
LAST UPDATED            : 199803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H18-N2-O3
MOLECULAR WEIGHT        : 262.34
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,4-Dihydro-6,7-dimethoxy-4-((dimethylamino)methylene)-3(2H)-isoquinolin
     one
   *   4-Dimethylaminomethylene-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-
     one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 77 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,324,1981
 
                            *** END OF RECORD ***