*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX6037200
CHEMICAL NAME           : 3(2H)-Isoquinolinone,
                          1,4-dihydro-4-(((2-(diethylamino)ethyl)amino)methylen
                          e)-6,7-dimethoxy-
CAS REGISTRY NUMBER     : 78915-25-0
BEILSTEIN REFERENCE NO. : 5641043
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H31-N3-O3
MOLECULAR WEIGHT        : 409.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1,4-Dihydro-4-(((2-(diethylamino)ethyl)amino)methylene)-6,7-dimethoxy-3(
     2H)-isoquinolinone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 225 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - tremor
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,324,1981
 
                            *** END OF RECORD ***