*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX6036000
CHEMICAL NAME           : 3(2H)-Isoquinolinone,
                          1-((3,4-diethoxyphenyl)methyl)-6,7-diethoxy-2-methyl-
                          , hydrochloride
CAS REGISTRY NUMBER     : 37528-72-6
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H31-N-O5.Cl-H
MOLECULAR WEIGHT        : 462.03
WISWESSER LINE NOTATION : T66 CNVJ B1R CO2 DO2& C1 HO2 IO2 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6,7-Diethoxy-1-(3,4-diethoxybenzyl)-2-methyl-3(2H)-isoquinolone  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,1131,1972
 
                            *** END OF RECORD ***