*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5948000
CHEMICAL NAME           : 8-Isoquinolinol, 1,2,3,4-tetrahydro-6,7-dimethoxy-,
                          hydrochloride
CAS REGISTRY NUMBER     : 2245-90-1
LAST UPDATED            : 199707
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C11-H15-N-O3.Cl-H
MOLECULAR WEIGHT        : 245.73
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Anhalamin hydrochloride
   * Anhalamine hydrochloride
   * N-Demethylanhalidine hydrochloride
   * 6,7-Dimethoxy-1,2,3,4-tetrahydro-8-isoquinolinol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 960 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   49,403,1966
 
                            *** END OF RECORD ***