*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5070500
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-6,7-dimethoxy-2-(2-piperidinoethxy
                          )-, dihydrochloride
CAS REGISTRY NUMBER     : 102395-78-8
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H28-N2-O2.2Cl-H
MOLECULAR WEIGHT        : 377.40
WISWESSER LINE NOTATION : T66 CNT&J HO1 IO1 C2- AT6NTJ &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(beta-Piperidinoetil)-6,7-dimetossi-1,2,3,4-tetraidroisochinoline  
   dicloridrato
   * 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-(2-piperidinoethyl)isoquinoline  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,562,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 15,562,1960
 
                            *** END OF RECORD ***