*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX5018100
CHEMICAL NAME           : Isoquinoline,
                          1,2,3,4-tetrahydro-6,7-dimethoxy-1-(3-indolylmethyl)-
                          2-((o-toluidino)methy l)-
CAS REGISTRY NUMBER     : 84218-41-7
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C28-H31-N3-O2
MOLECULAR WEIGHT        : 441.62
WISWESSER LINE NOTATION : T66 CNT&J C1MR B1& HO1 IO1 B1- DT56 BMJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   6,7-Dimethoxy-1-(3-indolylmethyl)-2-((o-toluidino)methyl)-1,2,3,4-tetrah
     ydroisoquinoline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - proteases
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,1233,1982
 
                            *** END OF RECORD ***