*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX0720000
CHEMICAL NAME           : Isoquinoline,
                          1-(4-ethoxy-3-methoxybenzyl)-6,7-dimethoxy-3-methyl-,
                          phosphate
CAS REGISTRY NUMBER     : 6670-95-7
LAST UPDATED            : 199309
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H25-N-O4.xH3-O4-P
MOLECULAR WEIGHT        : 1053.48
WISWESSER LINE NOTATION : T66 CNJ B1R DO2 CO1& D HO1 IO1 &QPQQO
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dioxyline phosphate
   * Dioxylium phosphate
   * 6,7-Dimethoxy-1-(4'-ethoxy-3'-methoxybenzyl)-3-methyl-isoquinoline,  
   phosphate
   * Isoquinoline, 6,7-dimethoxy-1-(4'-ethoxy-3'-methoxybenzyl)-3-methyl-,  
   phosphate
   * Paveril phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2069 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 40,207,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 113 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 40,207,1951
 
                            *** END OF RECORD ***