*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX0496000
CHEMICAL NAME           : Isoquinoline-6,7-diol, 1,2,3,4-tetrahydro-2-methyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 63937-92-8
LAST UPDATED            : 199009
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H13-N-O2.Cl-H
MOLECULAR WEIGHT        : 215.70
WISWESSER LINE NOTATION : T66 CNT&J C1 HQ IQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6,7-Dihydroxy-2-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride
   * Isoquinoline, N-methyl-6,7-dihydroxy-1,2,3,4-tetrahydro-, hydrochloride
   * N-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
   * 2-Methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 280 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - somnolence (general depressed activity)
   Skin and Appendages - hair
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 62,165,1938
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JCSOA9 Journal of the Chemical Society.  (London, UK)  1926-65.  For
   publisher information, see JCPRB4.  Volume(issue)/page/year: -,191,1947
 
                            *** END OF RECORD ***