*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX0350000
CHEMICAL NAME           : 6,7-Isoquinolinediol,
                          1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydro-,
                          hydrochloride
CAS REGISTRY NUMBER     : 3184-36-9
LAST UPDATED            : 199012
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H17-N-O4.Cl-H
MOLECULAR WEIGHT        : 323.80
WISWESSER LINE NOTATION : T66 CMT&J B1R CQ DQ& HQ IQ &GH
SYNONYMS/TRADE NAMES :
   * 1-Benzyl-3',4',6,7-tetrahydroxy-1,2,3,4-tetrahydroisoquinoline,  
   hydrochloride
   * Tetrahydropapaveroline, hydrochloride
   * THP hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 703 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 19,45,1967
 
                            *** END OF RECORD ***