*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NX0175000
CHEMICAL NAME           : Isoquinoline, 5-((p-(dimethylamino)phenyl)azo)-,
                          2-oxide
CAS REGISTRY NUMBER     : 10318-23-7
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H16-N4-O
MOLECULAR WEIGHT        : 292.37
WISWESSER LINE NOTATION : T66 CNJ CO GNUNR DN1&1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 5-((p-(Dimethylamino)phenyl)azo)isoquinoline 2-oxide
   * N,N-Dimethyl-4-(5'-isoquinolyl-2'-oxide)azoaniline
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 720 mg/kg/17W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumor types after systemic administration not seen
   spontaneously
REFERENCE :
   AICCA6 Acta Unio Internationalis Contra Cancrum.  (Louvain, Belgium) V.1-20,
   1936-64.  For publisher information, see IJCNAW. Volume(issue)/page/year:
   19,531,1963
 
                            *** END OF RECORD ***