*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NR3459000
CHEMICAL NAME : 2-Isoindolinebutyric acid, 1,3-dioxo-
CAS REGISTRY NUMBER : 3130-75-4
BEILSTEIN REFERENCE NO. : 0208243
REFERENCE : 5-21-10-00481 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C12-H11-N-O4
MOLECULAR WEIGHT : 233.24
WISWESSER LINE NOTATION : T56 BVNVJ C3VQ
COMPOUND DESCRIPTOR : Drug
Reproductive Effector
SYNONYMS/TRADE NAMES :
* 1,3-Dihydro-1,3-dioxo-2H-isoindole-2-butanoic acid
* 2H-Isoindole-2-butanoic acid, 1,3-dihydro-1,3-dioxo-
* 4-Phthalimidobuttersaure
* 4-Phthalimidobutyric acid
* N-Phthaloyl GABA
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 327 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information
Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
Volume(issue)/page/year: 27,805,1989
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE : 400 mg/kg
SEX/DURATION : female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Specific Developmental Abnormalities - other developmental
abnormalities
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
28,680,1973
*** END OF RECORD ***