*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW7126000
CHEMICAL NAME           : 3-Isoquinolinecarboxylic acid,
                          1,2-dihydro-1-oxo-4-phenyl-2-(2-(1-pyrrolidinyl)ethyl
                          )-
CAS REGISTRY NUMBER     : 112392-91-3
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H22-N2-O3
MOLECULAR WEIGHT        : 362.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-Oxo-4-phenyl-2-(2-(1-pyrrolidinyl)ethyl)-1,2-dihydro-3-isoquinolinecar
     boxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   125,437,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   125,437,1986
 
                            *** END OF RECORD ***