*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW6995000
CHEMICAL NAME           : 3-Isoquinolinecarboxamide,
                          N-(2-(dimethylamino)ethyl)-1-methoxy-4-phenyl-
CAS REGISTRY NUMBER     : 78945-78-5
LAST UPDATED            : 199306
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H23-N3-O2
MOLECULAR WEIGHT        : 349.47
WISWESSER LINE NOTATION : T66 CNJ BO1 DVM2N1&1 ER
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(2-(Dimethylamino)ethyl)-1-methoxy-4-phenyl-3-isoquinolinecarboxamide
   * Dimetilamminoetilammido della 1-metossi-3-carbossi-4-fenilisochinolina
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 36,400,1981
 
                            *** END OF RECORD ***