*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NW6991000
CHEMICAL NAME           : 3-Isoquinolinecarboxamide,
                          1,2-dihydro-2,4-dimethyl-N-(2-(dimethylamino)ethyl)-1
                          -oxo-
CAS REGISTRY NUMBER     : 89929-04-4
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H21-N3-O2
MOLECULAR WEIGHT        : 287.40
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2,4-Dimethyl-N-(2-(dimethylamino)ethyl)-1-oxo-1,2-dihydro-3-isoquinoline
     carboxamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 680 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 39,229,1984
 
                            *** END OF RECORD ***