*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS9800000
CHEMICAL NAME           : Isopentyl alcohol, acetate
CAS REGISTRY NUMBER     : 123-92-2
BEILSTEIN REFERENCE NO. : 1744750
REFERENCE               : 4-02-00-00157 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 28
MOLECULAR FORMULA       : C7-H14-O2
MOLECULAR WEIGHT        : 130.21
WISWESSER LINE NOTATION : 1Y1&2OV1
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Acetic acid, isopentyl ester
   * Banana oil
   * Isoamyl acetate
   * Isoamylester kyseliny octove
   * Isoamyl ethanoate
   * Isopentyl acetate
   * 3-Methyl-1-butanol acetate
   * 3-Methylbutyl acetate
   * 3-Methyl-1-butyl acetate
   * 3-Methylbutyl ethanoate
   * Pear oil
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 32,1241,1981
 
TYPE OF TEST            : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 35 gm/m3
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Behavioral - food intake (animal)
   Kidney, Ureter, Bladder - proteinuria
REFERENCE :
   AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene.  (Berlin, Ger.)
   V.1-18, 1930-61.  For publisher information, see IAEHDW.
   Volume(issue)/page/year: 5,1,1933
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7422 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IMSUAI Industrial Medicine and Surgery.  (Northbrook, IL)  V.18-42, 1949-73.
    For publisher information, see IOHSA5.  Volume(issue)/page/year: 41,31,1972
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - general anesthetic
REFERENCE :
   AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene.  (Berlin, Ger.)
   V.1-18, 1930-61.  For publisher information, see IAEHDW.
   Volume(issue)/page/year: 5,1,1933

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 532 mg/m3 (100 ppm)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 100 ppm (525 mg/m3)
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,138,1971

   OSHA PEL (Gen Indu):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 100 ppm (525 mg/m3)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 100 ppm (525 mg/m3) JAN 1993
   
   OEL-BELGIUM:TWA 100 ppm (532 mg/m3) JAN 1993
   
   OEL-DENMARK:TWA 100 ppm (525 mg/m3) JAN 1993
   
   OEL-FRANCE:TWA 100 ppm (525 mg/m3) JAN 1993
   
   OEL-JAPAN:TWA 100 ppm (530 mg/m3) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 100 ppm (525 mg/m3) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 100 ppm (525 mg/m3) JAN 1993
   
   OEL-RUSSIA:TWA 100 ppm JAN 1993
   
   OEL-UNITED KINGDOM:TWA 100 ppm (525 mg/m3);STEL 125 ppm JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO ISOAMYL ACETATE-air:10H TWA 100 ppm
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 40370
       No. of Facilities: 11016 (estimated)
       No. of Industries: 93
       No. of Occupations: 75
       No. of Employees: 96405 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 40370
       No. of Facilities: 7677 (estimated)
       No. of Industries: 62
       No. of Occupations: 79
       No. of Employees: 97668 (estimated)
       No. of Female Employees: 32512 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Esters I, 1450
   
   NTP Carcinogenesis studies; selected, October 1997

 
                            *** END OF RECORD ***