*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS6180000
CHEMICAL NAME           : Isonipecotic acid,
                          1-(3-phenothiazin-10-ylpropyl)-4-phenyl-, ethyl
                          ester, hydrobromide
CAS REGISTRY NUMBER     : 14653-24-8
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C29-H32-N2-O2-S.Br-H
MOLECULAR WEIGHT        : 553.61
WISWESSER LINE NOTATION : T C666 BN ISJ B3- AT6NTJ DVO2 DR &EH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(3-Phenothiazin-10-ylpropyl)-4-phenylisonipecotic acid ethyl ester  
   hydrobromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
                            *** END OF RECORD ***