*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS5360000
CHEMICAL NAME           : Isonipecotic acid,
                          1-(4,4-diphenyl-3-butenyl)-4-phenyl-, ethyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 14106-90-2
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H33-N-O2.Cl-H
MOLECULAR WEIGHT        : 476.10
WISWESSER LINE NOTATION : T6NTJ A3UYR&R& DVO2 DR &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(4,4-Diphenyl-3-butenyl)-4-phenylisonipecotic acid ethyl ester  
   hydrochloride
   * 4-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-butenyl)-4-phenyl-, ethyl  
   ester hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
                            *** END OF RECORD ***