*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS5315000
CHEMICAL NAME           : Isonipecotic acid,
                          1-(3-(10,11-dihydro-5-dibenz(b,f)azepinyl)propyl)-4-p
                          henyl-, ethyl ester, hydrochloride
CAS REGISTRY NUMBER     : 14187-10-1
LAST UPDATED            : 199007
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C31-H36-N2-O2.Cl-H
MOLECULAR WEIGHT        : 505.15
WISWESSER LINE NOTATION : T C676 BN&T&J B3- AT6NTJ DVO2 DR &GH
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,627,1967
 
                            *** END OF RECORD ***