*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3421000
CHEMICAL NAME           : 1H-Isoindole-1,3(2H)-dione,
                          3a,4,7,7a-tetrahydro-2-(4-(2-(1-pyrrolidinyl)ethoxy)c
                          yclohexyl)-
CAS REGISTRY NUMBER     : 61356-06-7
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H30-N2-O3
MOLECULAR WEIGHT        : 346.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3a,4,7,7a-Tetrahydro-2-(4-(2-(1-pyrrolidinyl)ethoxy)cyclohexyl)-1H-isoin
     dole-1,3(2H)-dione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 33,115,1976
 
                            *** END OF RECORD ***