*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS5310000
CHEMICAL NAME           : Isonipecotic acid,
                          1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 35607-36-4
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C28-H28-N2-O2.Cl-H
MOLECULAR WEIGHT        : 461.04
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Difenoxine hydrochloride
   * Difenoxin hydrochloride
   * Diphenoxylic acid hydrochloride
   * 4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-,  
   monohydrochloride
   * R 15403
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 149 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,1633,1974
 
                            *** END OF RECORD ***