*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3410000
CHEMICAL NAME           : 1H-Isoindole-1,3(2H)-dione,
                          3a,4,7,7a-tetrahydro-2-(4-(2-(1-piperidinyl)ethoxy)ph
                          enyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 61356-04-5
LAST UPDATED            : 198712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H26-N2-O3.Cl-H
MOLECULAR WEIGHT        : 390.95
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3a,4,7,7a-Tetrahydro-2-(4-(2-(1-piperidinyl)ethoxy)phenyl)-1H-isoindole-
     1,3(2H)-dione HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 210 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 33,115,1976
 
                            *** END OF RECORD ***