*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS2030000
CHEMICAL NAME           : Isonicotinic acid,
                          2-(2-methyl-4-oxo-3,4-dihydro-3-quinazolinyl)ethyl
                          ester
CAS REGISTRY NUMBER     : 50840-27-2
BEILSTEIN REFERENCE NO. : 0823729
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H15-N3-O3
MOLECULAR WEIGHT        : 309.35
WISWESSER LINE NOTATION : T66 BVN ENJ D1 C2OV- DT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(2-Hydroxyethyl)-2-methyl-4(3H)-quinazolinone 4-pyridylformate
   * 4(3H)-Quinazolinone, 3-(2-hydroxyethyl)-2-methyl-, isonicotinate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle weakness
   Behavioral - muscle contraction or spasticity
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 7,626,1973
 
                            *** END OF RECORD ***