*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS1900000
CHEMICAL NAME           : Isonicotinic acid, imidazol-4-ylmethyl ester,
                          dihydrochloride
CAS REGISTRY NUMBER     : 20062-43-5
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C10-H9-N3-O2.2Cl-H
MOLECULAR WEIGHT        : 276.14
WISWESSER LINE NOTATION : T6NJ DVO1- DT5M CNJ &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Imidazole-4-methanol, isonicotinate (ester), dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 2,360,1968
 
                            *** END OF RECORD ***