*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3399382
CHEMICAL NAME           : 1H-Isoindole-1,3(2H)-dione,
                          4,5,6,7-tetrahydro-2-(7-fluoro-3,4-dihydro-3-oxo-4-
                          (2-propynyl)-2H-1,4-benzoxazin-6-yl)-
CAS REGISTRY NUMBER     : 103361-09-7
OTHER CAS REGISTRY NOS. : 141490-50-8
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H15-F-N2-O4
MOLECULAR WEIGHT        : 354.36
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Flumioxazin
   *   7-Fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4-(2-propynyl)-1,4-benzoxazin
     -3(2H)-one
   * S 53482
   * Sumisoya
   * V 53482
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 300 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   CGANE7 Congenital Anomalies.  (Nippon Senten Ijo Gakkai, 377-2 Ono-higashi,
   Osakasayama, Osaka-Fu 589 Japan)  V.27-    1987-  Volume(issue)/page/year:
   35,123,1995
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 gm/kg
SEX/DURATION            : female 12 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
   Reproductive - Specific Developmental Abnormalities - blood and lymphatic
   systems (including spleen and marrow)
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 54,237,1996
 
                            *** END OF RECORD ***