*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3886248
CHEMICAL NAME           : 1H-Isoindol-1-one,
                          2,3-dihydro-3-(2-amino-5-fluorophenyl)-2-(2-(diethyla
                          mino)ethyl)-, hydrochloride, hydrate (2:4:3)
CAS REGISTRY NUMBER     : 116870-92-9
LAST UPDATED            : 199806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H24-F-N3-O.2Cl-H
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(2-Amino-5-fluorophenyl)-2-(2-diethylaminoethyl)isoindolin-1-one HCl  
   hydrate (2:4:3)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4849441
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4849441
 
                            *** END OF RECORD ***