*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NR3885000
CHEMICAL NAME : 1H-Isoindol-1-one,
2-(2-(diethylamino)ethyl)-2,3-dihydro-3-phenyl-,
phosphate
CAS REGISTRY NUMBER : 26070-68-8
LAST UPDATED : 199204
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C20-H24-N2-O.xH3-O4-P
MOLECULAR WEIGHT : 994.46
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* 2-(2-(Diethylamino)ethyl)-2,3-dihydro-3-phenyl-1H-isoindol-1-one
phosphate
* 2-(beta-Diethylaminoethyl)-3-phenylphthalimidine phosphate
* Gitan
* Phthalimidine, 2-(2-(diethylamino)ethyl)-3-phenyl-, phosphate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 287 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 185,47,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 103 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 185,47,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 58 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - convulsions or effect on seizure threshold
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 185,47,1970
*** END OF RECORD ***