*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3398940
CHEMICAL NAME           : 1H-Isoindole-1,3(2H)-dione,
                          2-((4-oxo-3(4H)-quinazolinyl)methyl)-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 75159-42-1
LAST UPDATED            : 199212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H11-N3-O3.2Cl-H
MOLECULAR WEIGHT        : 378.23
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-((4-Oxo-3(4H)-quinazolinyl)methyl)-1H-isoindole-1,3(2H)-dione  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
REFERENCE :
   JICSAH Journal of the Indian Chemical Society.  (Indian Chemical Soc., 92,
   Acharya Prafulla Chandra Rd., Calcutta 700009, India)  V.5-     1928-
   Volume(issue)/page/year: 56,1226,1979
 
                            *** END OF RECORD ***