*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM2256500
CHEMICAL NAME           : Indolizine,
                          1,3-bis((4-(4-chlorophenyl)-1-piperazinyl)methyl)-2-p
                          henyl-
CAS REGISTRY NUMBER     : 58892-64-1
LAST UPDATED            : 198408
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C36-H37-Cl2-N5
MOLECULAR WEIGHT        : 610.68
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Bis((4-(4-chlorophenyl)-1-piperazinyl)methyl)-2-phenylindolizine
   * CDRI 71-215
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 14,38,1976
 
                            *** END OF RECORD ***