*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM2252000
CHEMICAL NAME           : 1-Indolizineacetic acid,
                          3-(p-chlorobenzoyl)-7-methoxy-2-methyl-
CAS REGISTRY NUMBER     : 35475-66-2
BEILSTEIN REFERENCE NO. : 0447164
REFERENCE               : 5-22-07-00427 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H16-Cl-N-O4
MOLECULAR WEIGHT        : 357.81
WISWESSER LINE NOTATION : T56 ANJ BVR DG& C1 D1VQ GO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(p-Chlorobenzoyl)-7-methoxy-2-methyl-1-indolizineacetic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Tumorigenic - active as anti-cancer agent
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 26,1059,1971
 
                            *** END OF RECORD ***