*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NP6313500
CHEMICAL NAME           : 5-Isobenzofurancarbonitrile,
                          1,3-dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluoroph
                          enyl)-
CAS REGISTRY NUMBER     : 59729-33-8
LAST UPDATED            : 199801
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H21-F-N2-O
MOLECULAR WEIGHT        : 324.43
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Citalopram
   *   1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofur
     ancarbonitrile
   * 1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
   * Lu 10-171
   * Nitalapram
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 348,339,1996
 
                            *** END OF RECORD ***