*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM9744500
CHEMICAL NAME           : 2-133-Interleukin 2 (human reduced), 125-L-serine-
CAS REGISTRY NUMBER     : 110942-02-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C690-H1115-N177-O203-S6
MOLECULAR WEIGHT        : 4323.18
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aldesleukin
   * Interleukin-2 (Recombinant human)
   * Proleukin
   * 125-L-Serine-2-133-interleukin 2 (human reduced)
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 9240 ug/kg/4W-I
TOXIC EFFECTS :
   Blood - changes in erythrocyte (RBC) count
   Blood - changes in leukocyte (WBC) count
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year: 36(1,
   Pt 2),273,1997
 
                            *** END OF RECORD ***