*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM9700000
CHEMICAL NAME           : Interferon-alpha-4 (human leucocyte)
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * IFN-alpha
   * Interferon-alpha-4
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 1429 iu/kg
TOXIC EFFECTS :
   Brain and Coverings - changes in cerebral spinal fluid
   Behavioral - somnolence (general depressed activity)
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   286,940,1983
 
                            *** END OF RECORD ***