*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3300000
CHEMICAL NAME           : Indol-4(5H)-one,
                          3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-
CAS REGISTRY NUMBER     : 7416-34-4
LAST UPDATED            : 199801
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H24-N2-O2
MOLECULAR WEIGHT        : 276.42
WISWESSER LINE NOTATION : T56 BM FV&TJ C1 D2 G1- AT6N DOTJ
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * En-1733A
   * Molindone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 714 ug/kg/D
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - antipsychotic
REFERENCE :
   34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
   Academic Press, Inc., 1969  Volume(issue)/page/year: -,402,1969
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 4285 ug/kg/3D-I
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - cyanosis
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   JCLPDE Journal of Clinical Psychiatry.  (Physicians Postgraduate Press,
   Inc., POB 240008, Memphis, TN 38124)  V.39-    1978-
   Volume(issue)/page/year: 47,607,1986
 
                            *** END OF RECORD ***