*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3256000
CHEMICAL NAME           : 2H-Indol-2-one,
                          1,3-dihydro-3,3-bis(4-(sulfooxy)phenyl)-7-methyl-,
                          disodium salt
CAS REGISTRY NUMBER     : 54935-04-5
LAST UPDATED            : 199106
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C21-H15-N-O3-S2.2Na
MOLECULAR WEIGHT        : 439.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bis(bisulphate) diester of 3,3-bis(p-hydroxyphenyl)-7-methyl-2-indolinone 
    disodium salt
   * DAN 603
   * 1,3-Dihydro-7-methyl-3,3-bis(4-(sulfooxy)phenyl)-2H-indole-2-one disodium 
    salt
   * Laxitex
   * Sulisatina sodium
   * Sulisatine sodium
   * Sulisatin sodium
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >4 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   13,327,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1440 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   13,327,1977
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   MDACAP Medicamentos de Actualidad.  (J.R. Prous, S.A., Apartado de Correos
   540, 08080 Barcelona, Spain)  V.1-    1965-  Volume(issue)/page/year:
   13,327,1977
 
                            *** END OF RECORD ***