*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3203000
CHEMICAL NAME           : Indol-5-ol, 3-(2-morpholinoethyl)-, hydrochloride
LAST UPDATED            : 198505
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H18-N2-O2.Cl-H
MOLECULAR WEIGHT        : 282.80
WISWESSER LINE NOTATION : T56 BMJ D2- AT6N DOTJ& GQ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Hydroxy-3-(beta-morpholinoethyl)indole hydrochloride
   * 3-(2-Morpholinoethyl)indol-5-ol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 14,247,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 14,247,1962
 
                            *** END OF RECORD ***