*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY6826000
CHEMICAL NAME           : L-Alanine,
                          gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl-
                          L-alanyl-
CAS REGISTRY NUMBER     : 35597-43-4
LAST UPDATED            : 199604
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H22-N3-O6-P
MOLECULAR WEIGHT        : 323.33
WISWESSER LINE NOTATION : QVY1&MVY1&MVYZ2PHO&1Q
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * L-Alanine, 4-(hydroxymethylphosphinyl)-L-2-aminobutanoyl-L-alanyl-
   * Antibiotic SF 1293
   * Bialaphos
   * Bilanafos
   * gamma-(Hydroxymethylphosphinyl)-L-alpha-aminobutyryl-L-alanyl-L-alanine
   * Phosphinothricylalanylalanine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),223,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),223,1980
 
                            *** END OF RECORD ***