*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY6650000
CHEMICAL NAME           : Alanine, 3-(3-hydroxyanthraniloyl)-, L-
CAS REGISTRY NUMBER     : 606-14-4
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N2-O4
MOLECULAR WEIGHT        : 224.24
WISWESSER LINE NOTATION : ZR BQ FV1YZVQ  -L
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Benzenebutanoic acid, alpha,2-diamino-3-hydroxy-gamma-oxo-, (S)-
   * 3-(3-Hydroxyanthraniloyl)-L-alanine
   * L-3-Hydroxykynurenine
   * 3-Hydroxy-L-kynurenine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4408 mg/kg/21D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - bronchiogenic carcinoma
REFERENCE :
   JCROD7 Journal of Cancer Research and Clinical Oncology.  (Springer-Verlag
   New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.93-
   1979-  Volume(issue)/page/year: 96,163,1980
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Tumorigenic - facilitates action of known carcinogen
REFERENCE :
   ANYAA9 Annals of the New York Academy of Sciences.  (New York Academy of
   Sciences, 2 E. 63rd St., New York, NY 10021)  V.1-    1877-
   Volume(issue)/page/year: 108,924,1963
 
                            *** END OF RECORD ***