*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL3665000
CHEMICAL NAME           : 1H-Indole-3-acetic acid,
                          2-methyl-1-(3,4-methylenedioxybenzoyl)-5-methoxy-
CAS REGISTRY NUMBER     : 21722-66-7
BEILSTEIN REFERENCE NO. : 0500638
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H17-N-O6
MOLECULAR WEIGHT        : 367.38
WISWESSER LINE NOTATION : T56 BO DO CHJ GV- BT56 BNJ C1 D1VQ GO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Compound ID-955
   * ID-955
   * 2-Methyl-1-(3,4-methylenedioxybenzoyl)-5-methoxy-1H-indole-3-acetic acid
   * 1-(3',4'-Methylendioxybenzoyl)-2-methyl-5-methoxy-3-indoyl-essigsaeure
   * 1-(3',4'-Methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 440 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,981,1969
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,981,1969
 
                            *** END OF RECORD ***